INTERNATIONAL CONGRESS ON RECENT ADVANCES IN SCIENCES AND TECHNOLOGY - Kuala Lumpur - Malaysia (2019-02-20)

Development of multi-compartment biokinetic model for internal radiation dosimetry by using MATLAB
Internal radiation hazards result from radioactive substances that gets inside the human body when breathe it or eat it or when it passes through skin. Internal radionuclides produce radiation doses the entire time they are in the body until the radioactive material is no longer radioactive (it decays) or is removed naturally by the body.All radionuclides are potentially hazardous if inhaled or ingested. The internal doses for workers or members of the public exposed to the intake of radioactive particulates can be estimated using bioassay data such as lung and body counter measurements, urine or faecal radioisotope concentration, etc. The International Commission on Radiological (ICRP) biokinetic models are applied to establish a relationship between the individual intake and the bioassay measurements, and then to infer the internal dose. For internal dosimetry, biokinetic modeling is commonly used in order to evaluate bioassay data. Generally, computer programs can be used for bioassay evaluations. The radiation doses resulting from internally deposited radionuclide from radioactive cannot be measured directly. Occupational radiation workers are monitored by making systematic measurements of activity concentrations in air, activity in the body or excretion rates. The correct quantitative interpretation of such measured values requires well-defined biokinetic mathematical models and data describing the behaviour of radioactive materials in the human body. Biokinetic models and comprehensive data are provided by the ICRP. The objective of this study is to develop a multi-compartment biokintic model for calculation of internal radiation doses to different organs from target organ. A computer program has been developed based on MATLAB software for calculation of tissue doses of radiation workers. In the multi-compartmental biokinetic model, human organs or tissues are grouped into many compartments to perform calculations. A mathematical algorithm has been used for calculation of radionuclide retention and elimination Based on retention function for radionuclide of interest, the tissue doses have calculated through biokinetic model. The results of the present study are benchemarked by using MONDAL/IDAC computer software.
Professor Abdus Sattar Mollah, Ms. Shanjida Akter, Ms. Shamsun Nahar Raka, Ms. Sunjida Jahan