3RD INTERNATIONAL CONGRESS ON TECHNOLOGY - ENGINEERING & SCIENCE - Kuala Lumpur - Malaysia (2017-02-09)

Synthesis And Properties Of Benzoquinazolines, Spirocondensed With Cycloheptane Cycle

By cyclization of ethyl 2-(1-benzylcycloheptyl)-2-cyanoacetate synthesis method of ethyl 4'-amino-1'H-spiro[cycloheptane-1,2'-naphthalene]-3'-carboxylate (aminoester) was developed. In the basis of aminoester biologically active (antitumor, antimonoaminoxidaze, antibacterial) benzoquinazolines spirocondensed with cycloheptane cycle were obtained.
Ashot Markosyan, Siranush Gabrielyan, Avetik Markosyan, Flora Arsenyan, Hrachik Stepanyan, Rima Sukasyan