3RD INTERNATIONAL CONGRESS ON TECHNOLOGY - ENGINEERING & SCIENCE - Kuala Lumpur - Malaysia (2017-02-09)

Scrutinizing Acute And Chronic Toxicological Impinge Of Atrazine (1-chloro-3-ethylamino-5-isopropylamino-2, 4, 6-triazine) On Aquatic Organisms Through Evaluating Stress Biomarker; Plasma Glucose Concentration Of Fresh Water Fish; Grass Carp, (ctenopharyngodon Idella)
Herbicide praxis in agricultural fields to curb herbs is utterly toxic to non target areas like aquatic bodies and impinge aquatic organism distinctively fish health through impairment of metabolism, sometimes leading to mortality. So for contemplation of acute (short term) and chronic (long term) toxicological effects of atrazine, study was designed to determines the potential detrimental effects of commercial utilization of chemical named; atrazine, on aquatic organisms through evaluating stress biomarker; plasma glucose (energy currency) of freshwater fish; grass carp, (Ctenopharyngodon idella) for 01(24), 02(48), 03(72), 04(96), 10(240), 15(360) and 15(600) days(hrs) under the dose 15µl/L, 13µl/L, 10µl/L and 08µl/L, 06µl/L, 04µl/L, 02µl/L respectively. Above 15µl/L LC50 was recorded indicating grass carp sensitivity to atrazine. Control group concentration of plasma glucose was 42.3mmol/L. Paramount downturn during acute toxicity and chronic toxicity was observed after 24hrs (15µl/L) and 240hrs (06µl/L) exposure respectively among treated groups while in both groups with the declining of dose quantity an inclined in glucose concentration was observed. Downturn in concentration could be attributed to the toxic effect of atrazine on the liver and upturn in concentration may be due to inhibition of the gluconeogenesis process which enhances glycogen breakdown in the liver and consequently elevates blood glucose level in response of stress to cope with new environmental conditions. Our study is also purposive to fathom that atrazine is causing agent of acute and chronic health problem to aquatic organisms and induced stress in fish body which revealed pessimistic domination on ecosystem of the aquatic organisms.
Ahsan Khan, Nazish Shah, Muhammad Adnan, Shahibzada Muhammad Jawad, Ali Muhammad Yousafzai